Banjo's House is located in Spiral Mountain, and in a greater scale, the Isle O' Hags. As its name implies, it is where Banjo and Kazooie live. It has appeared in every game in the Banjo-Kazooie series to date, except for Banjo-Pilot. In Banjo-Kazooie, Banjo and Kazooie are inside sleeping, when Tooty comes to visit and ends up getting kidnapped by Gruntilda. In Banjo-Tooie, Banjo, Kazooie, Mumbo Jumbo, and Bottles are playing cards inside on a dark and stormy night. When Grunty is freed by her sisters from underneath the rock, she fires a spell at Banjo's house, destroying it and killing Bottles (who stayed inside when the others escaped) in the process. Banjo's house appears only briefly in the opening scene of Banjo-Kazooie: Grunty's Revenge.

In Banjo-Kazooie: Nuts & Bolts, Banjo and Kazooie are sitting outside of it, listening to the radio, with Kazooie playing a game with an Xbox 360 controller and headset. They never bothered to finish repairing it after the events of Banjo-Tooie. At the end of Nuts & Bolts, the house is repaired and painted pink by Jolly Dodger. Banjo's house has also been used as the main menu in each of the console games.

Inside Banjo's house is a bed, a fishbowl containing Roysten, his pet goldfish, a fireplace (with a picture of Bottles above the mantle), a stove, a blue couch, Banjo's bed with a hat hanger where he puts his backpack (and Kazooie), and a picture of Tooty. In Banjo-Kazooie: Nuts & Bolts, a stack of Xbox 360s are seen and a box containing Kazooie's moves from the previous games can also be seen if the player defeats Gruntilda at the end of the game.